Author

Mauricio J.A. Ruiz-Fernandez

Institut für Chirurgische ForschungORCID 0000-0001-9693-1317Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Jack MerriniD· 2 shared Jörg RenkawitziD· 2 shared Alice BattistellaiD· 1 shared Andreas W. ThomaeiD· 1 shared Armina MortazaviiD· 1 shared Artur Kuznetcov· 1 shared Benedikt SabassiD· 1 shared Bingzhi WangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Jack MerrinORCID

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2 papers

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedApr 25, 2025

Mechanical Centrosome Fracturing during Cell Navigation

Madeleine T. Schmitt, Janina Kroll, Mauricio J.A. Ruiz-Fernandez…·Jörg Renkawitz

The paper shows that centrosomes in non-dividing cells can fracture under mechanical stress during cell navigation, and Dyrk3 prevents this fracturing to maintain cellular function.

7 citations

experimental assaycell signaling & trafficking

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Cell BiologybioRxivPreprintMay 3, 2024

Size-Dependent Mechanoadaptation Enables Migration with Oversized Parasitic Cargo

Mauricio J.A. Ruiz-Fernandez, Jianfei Jiang, Alice Battistella…·Jörg Renkawitz

The paper investigates how cells adapt to transport oversized parasitic cargo by reprogramming mechanical forces and subcellular architecture during migration.

3 citations

mouseimaging

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