Samuel A. Rose

This study identifies PD-L2's role on dendritic cells in restraining CD8+ T cell immunity in tumors, showing distinct functions from PD-L1 and suggesting therapeutic implications for PD-L2 blockade.

The paper introduces Suco and Compocyte to classify immune cells from 3,965 patients, identifying new macrophage and monocyte states and T cell memory erosion in metastases.

This study shows that CSF-1 signaling is essential for cerebellar microglia identity and function, and its disruption causes motor and social behavior defects.

This study examines the contribution of protein-coding de novo mutations to schizophrenia risk using whole-exome sequencing data from parent-offspring trios, finding a modest but polygenic effect.