Author

Fiona A. Desland

Tisch Cancer InstituteORCID 0000-0001-7516-3160Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Christie ChangiD· 2 shared Miriam MéradiD· 2 shared Yonit LaviniD· 2 shared Aleksandra WroblewskaiD· 1 shared Alessia BaccariniiD· 1 shared Alexandra L. JoyneriD· 1 shared Alexandra TabachnikovaiD· 1 shared Alice Oliffson KamphorstiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Christie ChangORCID

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2 papers

Recent·Most cited

TREM2 macrophages are associated with enhanced response to PD-1 blockade in human hepatocellular carcinoma

Pauline Hamon, Matthew D. Park, Jessica Le Bérichel, Merav Cohen, Brian Y. Soong, Mark Buckup, Clotilde Hennequin, Katherine E. Lindblad, Raphaël Mattiuz, Igor Figueiredo, Alexandra Tabachnikova, Travis Dawson, Darwin D’souza, Leanna Troncoso, Giorgio Ioannou, , Miriam Mérad

The paper identifies TREM2-expressing macrophages as predictors of response to PD-1 blockade in HCC patients using clinical and spatial transcriptomic data.

bioRxiv · Sep 9, 2025 · PreprintImmunology

Disruption of the CSF-1-CSF-1R axis alters cerebellar microglia and is associated with motor and social interaction defects

Veronika Kana, Fiona A. Desland, María Casanova-Acebes, Pinar Ayata, Ana Badimon, Elisa M. Nabel, Kazuhiko Yamamuro, Marjolein A. M. Sneeboer, I‐Li Tan, Meghan E. Flanigan, Samuel A. Rose, Christie Chang, Andrew M. Leader, Hortense Le Bourhis, Eric S. Sweet, , Miriam Mérad

This study shows that CSF-1 signaling is essential for cerebellar microglia identity and function, and its disruption causes motor and social behavior defects.

The Journal of Experimental Medicine · Jul 26, 2019Peer-reviewedNeuroscience