Author

Takahiro Higuchi

Universitätsklinikum WürzburgORCID 0000-0001-9711-7835Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:experimental assay· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Christoph MaackiD· 2 shared Ahmadali Lotfinia· 1 shared Alexander G. NickeliD· 1 shared Andressa G. AmaraliD· 1 shared Anja KarlstaedtiD· 1 shared Bruce MorganiD· 1 shared Caroline Bickelmann· 1 shared Christopher CarleiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

Christoph MaackORCID

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2 papers

Recent·Most cited

PhysiologyDiabetologiaPeer-reviewedOct 24, 2025

Pancreatic islets undergo functional and morphological adaptation during development of Barth Syndrome

Christopher Carlein, Markus D. A. Hoffmann, Caroline Bickelmann…·Letícia Prates Roma

The paper investigates how defective cardiolipin remodeling in Barth Syndrome affects pancreatic islet function and metabolism, finding improved glucose tolerance and compensatory metabolic adaptations in a mouse model.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 31, 2025

Interferon gamma signaling drives cardiac metabolic rewiring

Ebram Tharwat Melika, DiyaaElDin Ashour, Kyoungmin Kim…·Gustavo Campos Ramos

This study shows that IFN-gamma signaling in cardiomyocytes causes metabolic changes in the heart, including increased glucose uptake and reduced oxidative phosphorylation, which resemble changes in aging and heart failure.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky