Author

Ebram Tharwat Melika

Universitätsklinikum Würzburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander G. NickeliD· 1 shared Anja KarlstaedtiD· 1 shared Christoph MaackiD· 1 shared DiyaaElDin AshouriD· 1 shared Edécio Cunha‐NetoiD· 1 shared Georg GasteigeriD· 1 shared Gustavo Campos RamosiD· 1 shared Kyoungmin KimiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexander G. NickelORCID

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1 paper

Recent·Most cited

Interferon gamma signaling drives cardiac metabolic rewiring

Ebram Tharwat Melika, DiyaaElDin Ashour, Kyoungmin Kim, Alexander G. Nickel, Paula-Anahi Arias-Loza, Xinyu Chen, Panagiota Arampatzi, Mugdha Srivastava, Martin Väth, Edécio Cunha‐Neto, Michaela Kühn, Georg Gasteiger, Ulrich Hofmann, Takahiro Higuchi, Christoph Maack, , Gustavo Campos Ramos

This study shows that IFN-gamma signaling in cardiomyocytes causes metabolic changes in the heart, including increased glucose uptake and reduced oxidative phosphorylation, which resemble changes in aging and heart failure.

bioRxiv · Aug 31, 2025 · PreprintImmunology