Author

Liana N. Merk

Harvard UniversityORCID 0000-0001-9711-954XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrey ShuriD· 1 shared Douglas K. BrubakeriD· 1 shared Javier Muñoz BrionesiD· 1 shared Leopold N. GreeniD· 1 shared Richard M. MurrayiD· 1 shared Sean R. EddyiD· 1 shared Smrutiti JenaiD· 1 shared Thomas A Jones· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperSynthetic Biology

Andrey ShurORCID

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2 papers

Recent·Most cited

BioinformaticsNucleic Acids ResearchPeer-reviewedJul 27, 2025

Prevalence of Group II Introns in Phage Genomes

Liana N. Merk, Thomas A Jones, Sean R. Eddy

This study identifies group II introns in phage genomes using RNA structure-based homology searches, revealing their prevalence across diverse phage lineages.

6 citations

statistical modeldatabase / resource

𝕏 PostBluesky

Synthetic BiologyACS Synthetic BiologyPeer-reviewedNov 28, 2024

Diagnostic and Therapeutic Microbial Circuit with Application to Intestinal Inflammation

Liana N. Merk, Andrey Shur, Smrutiti Jena…·Leopold N. Green

This paper engineers a synthetic microbial circuit in E. coli to respond to two signals and secrete IL-22 for anti-inflammatory effects in a gut epithelial model.

3 citations

humanCRISPR screen

𝕏 PostBluesky