Author

Joseph O. Primeau

University of AlbertaORCID 0000-0001-9734-3736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Carlos Cruz‐CortésiD· 1 shared Howard S. YoungiD· 1 shared L. Michel Espinoza‐FonsecaiD· 1 shared M. Joanne LemieuxiD· 1 shared Vinh H. Nguyen· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

Carlos Cruz‐CortésORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintFeb 6, 2026

Supercharging the calcium pump: Identification of an activation hotspot on SERCA by cryo-EM.

Vinh H. Nguyen, Carlos Cruz‐Cortés, Joseph O. Primeau…·Howard S. Young

This paper identifies an activation hotspot on SERCA using cryo-EM structures of SERCA bound to two activators, revealing structural insights for rational drug design.

DOI 10.64898/2026.02.05.703879

experimental assayprotein structure prediction

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