BiophysicsbioRxivPreprint
Supercharging the calcium pump: Identification of an activation hotspot on SERCA by cryo-EM.
Vinh H. Nguyen, Carlos Cruz‐Cortés, Joseph O. Primeau…·Howard S. Young
This paper identifies an activation hotspot on SERCA using cryo-EM structures of SERCA bound to two activators, revealing structural insights for rational drug design.
DOI 10.64898/2026.02.05.703879