Author
University of MünsterORCID 0000-0001-9740-0788Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Lara Marie Siebert-Kuss, Henrike Krenz, Tobias Tekath…·Sandra Laurentino
The paper analyzes transcriptomes of human testis with different germ cell arrest stages to identify gene and transcript dynamics during spermatogenesis.
Ulrike Anne Friedrich, Marc Bienias, Claudia Zinke…·Franziska Auer
The paper evaluates clinical checklists for genetic testing in pediatric oncology, finding low specificity and missing 25% of children with cancer predisposition variants.
Malte D. Luecken, Maren Büttner, Kridsadakorn Chaichoompu…·Fabian Joachim Theis
BBKNN, Scanorama, and scVI lead complex scRNA-seq integration in a 38-setup, nine-task, 14-metric benchmark; highly variable gene selection helps, whereas scaling favors batch removal over bio-conservation.
Sara Di Persio, Tobias Tekath, Lara Marie Siebert-Kuss…·Nina Neuhaus
The paper identifies EGR4-dependent UTF1 downregulation as a factor in reduced reserve spermatogonial stem cells in infertile men, linked to altered chromatin structure.
Margot Julia Wyrwoll, Şehime Gülsün Temel, Liina Nagirnaja…·Frank Tüttelmann
The paper identifies biallelic M1AP mutations as a cause of meiotic arrest and male infertility through whole exome sequencing and cohort screening.
Henrike Krenz, Jörg Gromoll, Thomas Darde…·Frank Tüttelmann
The Male Fertility Gene Atlas aggregates and integrates OMICs data from publications on male infertility to enable targeted search and meta-analysis of genetic and epigenetic factors.
Elsa Leitão, Sara Di Persio, Sandra Laurentino…·Bernhard Horsthemke
The paper investigates DNA methylation patterns in sperm from infertile men and finds that somatic DNA contamination and genetic variation, rather than recurrent epimutations, explain observed methylation abnormalities.