Ulrike Anne Friedrich

The paper shows that tissue composition at the amputation plane influences osteoclast-mediated skeletal resorption and regenerative strategies in axolotl limb regeneration.

The paper shows that passage 1 human iPSC-derived RPE cells form more extensive monolayers after transplantation compared to passage 2 cells, highlighting a subpopulation with higher transplantation potential.

The paper evaluates clinical checklists for genetic testing in pediatric oncology, finding low specificity and missing 25% of children with cancer predisposition variants.

The paper investigates the distinct physiological roles of NatA and NatB in S. cerevisiae through transcriptome, translatome, and proteome profiling of mutants, revealing specific effects on gene expression and protein folding.

The paper identifies amino acid pairs at the ribosome's P- and A-sites that predictably and causally modulate translation-elongation rates in yeast.

The paper develops chemical kinetic methods to measure translation initiation, elongation, and codon-specific rates from ribosome profiling data, finding significant variability in codon translation rates.