Marius Wöste

This study identifies transcriptional states and regulators of spermatogonial stem cell differentiation in marmoset testes across developmental stages.

The paper analyzes transcriptomes of human testis with different germ cell arrest stages to identify gene and transcript dynamics during spermatogenesis.

This study shows TRIM71 is essential for germ cell development in mice and links TRIM71 variants to human male infertility.

The paper identifies biallelic M1AP mutations as a cause of meiotic arrest and male infertility through whole exome sequencing and cohort screening.

The paper investigates DNA methylation patterns in sperm from infertile men and finds that somatic DNA contamination and genetic variation, rather than recurrent epimutations, explain observed methylation abnormalities.

wg-blimp is an end-to-end pipeline for whole genome bisulfite sequencing data analysis that improves upon existing tools by offering a comprehensive workflow and interactive interface, validated on public datasets.