Kimberly J. Dunham‐Snary

The paper identifies circ5078 as a BMPR2-derived circular RNA that regulates endothelial proliferation and stress responses in PAH, with opposing effects to linear BMPR2 mRNA.

This paper shows that NDUFS2 in mitochondrial Complex I is critical for oxygen responsiveness in human DASMCs, affecting calcium, cell shortening, and mROS without altering respiration.

This study identifies mtDNA- and diet-specific metabolite profiles in a mouse model of cardiometabolic disease, revealing nDNA-mtDNA interactions that influence metabolic pathways and insulin resistance.

The paper shows that platelet mitochondrial bioenergetics correlate with skeletal muscle mitochondrial function in mice, suggesting platelets as a non-invasive surrogate for muscle metabolism assessment.

Confidence is a web app that performs differential gene expression analysis, gene scoring, and enrichment analysis to prioritize genes for further investigation.