Author

Jeffrey D. Mewburn

Queen's UniversityORCID 0000-0002-1365-4228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kimberly J. Dunham‐SnaryiD· 2 shared Stephen L. ArcheriD· 2 shared Amber L. SimpsoniD· 1 shared Ami WangiD· 1 shared Andrew GarveniD· 1 shared Andrew W. CraigiD· 1 shared Anna Ryan HemnesiD· 1 shared Anne L. TheilmanniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Kimberly J. Dunham‐SnaryORCID

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3 papers

Recent·Most cited

Circular RNA profiling identifies circ5078 as a BMPR2-derived regulator of endothelial proliferation and stress responses

M. Martin VandenBroek, M.C. Sharp, Patrick Thompson, Emmanuel Fagbola, Douglas Quilty, Jeffrey D. Mewburn, Anne L. Theilmann, Kimberly J. Dunham‐Snary, Anna Ryan Hemnes, Joy D. Cogan, Eric D. Austin, Rizwan Hamid, Stephen L. Archer, Neil M. Renwick, Mark L. Ormiston

The paper identifies circ5078 as a BMPR2-derived circular RNA that regulates endothelial proliferation and stress responses in PAH, with opposing effects to linear BMPR2 mRNA.

Arteriosclerosis Thrombosis and Vascular Biology · Aug 7, 2025Peer-reviewedMolecular Biology

The Core Subunit NDUFS2 in Mitochondrial Electron Transport Chain Complex I is Critical to Oxygen Responsiveness of Human Ductus Arteriosus Smooth Muscle Cells

Rachel E. T. Bentley, Kimberly J. Dunham‐Snary, Ashley Y Martin, Jeffrey D. Mewburn, Asish Dasgupta, Kuang‐Hueih Chen, Benjamin P. Ott, Tanvi Nandani, Bernard Thébaud, Mark Kevin Friedberg, Charles C.T. Hindmarch, Stephen L. Archer

This paper shows that NDUFS2 in mitochondrial Complex I is critical for oxygen responsiveness in human DASMCs, affecting calcium, cell shortening, and mROS without altering respiration.

bioRxiv · Jul 8, 2025 · PreprintMolecular Biology

Fes-deficient macrophages enhance CD8+ T cell priming and tumour control through increased proinflammatory cytokine production and localization

Brian J. Laight, Danielle Harper, Natasha Dmytryk, Connie S. Zhang, Changnian Shi, Andrew Garven, Richard W. Nauman, Jacob LK Kment, Faizah Alotaibi, Іван Шаповалов, Victoria Hoskin, Yan Gao, Jeffrey D. Mewburn, Caitlyn Vlasschaert, Ami Wang, , Peter A. Greer

Cancer Research · Apr 29, 2025Peer-reviewedImmunology