Mark L. Ormiston

This study shows that NK cell TGF-β signaling regulates postnatal lung development and BPD by affecting vascular patterning and senolytic activity.

The paper introduces a semi-automated method using Fiji to quantify lung airway and alveolar features in a mouse model of BPD, showing correlations with mean linear intercept and demonstrating structural changes in hyperoxia-exposed mice.

The paper identifies circ5078 as a BMPR2-derived circular RNA that regulates endothelial proliferation and stress responses in PAH, with opposing effects to linear BMPR2 mRNA.

This study evaluates Drpitor1a, a Drp1 inhibitor, showing efficacy in reducing PAH in female rats and human PASMCs without toxicity.