Scientific Communication & EducationbioRxivPreprint
A National Survey of 205 Canadian Biomedical Research Core Facilities Reveals Structural Challenges and Opportunities for Strengthening Canada's Research Ecosystem
DOI 10.64898/2026.06.29.732987
Author
Stephen L. Archer
Queen's UniversityORCID 0000-0003-1106-3202Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 24 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 shared papersScientific Communication & Education
Charles C.T. HindmarchORCID
Mutual co-authors in cluster
7 papers
Recent·Most cited
- GenomicsbioRxivPreprint
Pulmonary Hypertension Engine for Linked Experiments (PHELEX): a platform for the re-analysis of public transcriptomic data related to pulmonary hypertension in both animal models, and humans.
Tanvi Nandani, Benjamin P. Ott, Prusha Balaratnam…·Charles C.T. Hindmarch
PHELEX provides a searchable repository of RNA sequencing data for pulmonary hypertension, enabling analysis and cross-study comparisons to uncover molecular signatures.
- Molecular BiologybioRxivPreprint
Levosimendan Ameliorates Adverse Pulmonary Vascular Remodeling in Group-2 Pulmonary Hypertension.
Antonella Abi-Sleimen, Ruaa Al‐Qazazi, Yann Grobs…·François Potus
This study develops preclinical models of Group-2 pulmonary hypertension and shows that levosimendan improves cardiac function and reduces pulmonary vascular inflammation and remodeling.
DOI 10.1101/2025.10.23.684000 - Molecular BiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
Circular RNA profiling identifies circ5078 as a BMPR2-derived regulator of endothelial proliferation and stress responses
M. Martin VandenBroek, M.C. Sharp, Patrick Thompson…·Mark L. Ormiston
The paper identifies circ5078 as a BMPR2-derived circular RNA that regulates endothelial proliferation and stress responses in PAH, with opposing effects to linear BMPR2 mRNA.
3 citations - Molecular BiologybioRxivPreprint
The Core Subunit NDUFS2 in Mitochondrial Electron Transport Chain Complex I is Critical to Oxygen Responsiveness of Human Ductus Arteriosus Smooth Muscle Cells
Rachel E. T. Bentley, Kimberly J. Dunham‐Snary, Ashley Y Martin…·Stephen L. Archer
This paper shows that NDUFS2 in mitochondrial Complex I is critical for oxygen responsiveness in human DASMCs, affecting calcium, cell shortening, and mROS without altering respiration.
DOI 10.1101/2025.07.08.663799 - Genetic & Genomic MedicineGenetics in MedicinePeer-reviewed
Defining the Clinical Validity of Genes Reported to Cause Pulmonary Arterial Hypertension
Carrie L. Welch, Micheala A. Aldred, Srimmitha Balachandar…·Dmitry A. Zateyshchikov
This paper classifies PAH-related genes based on evidence strength using a semi-quantitative scoring system, identifying twelve genes with definitive evidence and recommending their inclusion in genetic testing panels.
83 citationstop 1% - GeneticsGenome MedicinePeer-reviewed
Rare variant analysis of 4,241 pulmonary arterial hypertension cases from an international consortium implicate FBLN2, PDGFD and rare de novo variants in PAH
Na Zhu, Emilia M. Swietlik, Carrie L. Welch…·National Cohort Study of Idiopathic and Heritable PAH
This study identifies two new PAH risk genes, FBLN2 and PDGFD, through rare variant analysis of 4,241 PAH cases, with de novo variants contributing to ~15% of pediatric IPAH.
84 citationstop 1%