Jiro Yoshino

Coupled transcriptomic divergence establishes a human-specific synaptic glial precursor state

The paper identifies a human-specific synaptic glial precursor state by analyzing single-cell differentiation trajectories across multiple species and shows its role in human cortical evolution.

Heat-off responses of epidermal cells sensitize Drosophila larvae to noxious inputs

This study shows that Drosophila larval epidermal cells, not nociceptors, mediate heat-induced sensitization to noxious stimuli through thermosensitive calcium responses involving Orai and Stim.

Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs

The paper shows that Drosophila epidermal cells are mechanosensitive and modulate nociceptive behaviors by activating sensory neurons and altering responses to mechanical stimuli.

Dendrite intercalation between epidermal cells tunes nociceptor sensitivity to mechanical stimuli in Drosophila larvae