Jay Z. Parrish

Altering cell size asymmetry in Drosophila neural stem cells creates supernumerary stem cells with limited lineage expansion potential

The paper investigates how altering cell size asymmetry in Drosophila neural stem cells affects their proliferation and lineage potential, finding increased stem cell pools but reduced lineage size and differentiation.

The engulfment receptor Draper is required for epidermal dendrite ensheathment

The paper identifies Draper as a receptor in epidermal cells that mediates neurite ensheathment through recognition of phosphatidylserine on neurons.

Heat-off responses of epidermal cells sensitize Drosophila larvae to noxious inputs

This study shows that Drosophila larval epidermal cells, not nociceptors, mediate heat-induced sensitization to noxious stimuli through thermosensitive calcium responses involving Orai and Stim.

Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs

The paper shows that Drosophila epidermal cells are mechanosensitive and modulate nociceptive behaviors by activating sensory neurons and altering responses to mechanical stimuli.

Axon length-dependent synapse loss is mediated by neuronal cytokine-induced glial phagocytosis

The paper identifies cytokine signaling from neurons to glia as a key determinant in axon length-dependent vulnerability in fly models of human neurodegenerative disorders.

Dendrite intercalation between epidermal cells tunes nociceptor sensitivity to mechanical stimuli in Drosophila larvae

A cell atlas of the larval Aedes aegypti ventral nerve cord

This study creates a cell atlas of the larval Aedes aegypti ventral nerve cord using scRNA-seq, identifying over 35 cell types and linking larval and adult VNC composition.

A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites

This study identifies a conserved morphogenetic mechanism by which epidermal cells ensheath somatosensory neurites, contributing to nociceptive function in Drosophila and zebrafish.

Modulation of host learning in Aedes aegypti mosquitoes

This study shows that aversive olfactory learning influences mosquito host preference, with dopamine playing a key role in modulating olfactory responses.