Federico Marcello Tenedini

This study shows that Drosophila larval epidermal cells, not nociceptors, mediate heat-induced sensitization to noxious stimuli through thermosensitive calcium responses involving Orai and Stim.

The paper identifies cytokine signaling from neurons to glia as a key determinant in axon length-dependent vulnerability in fly models of human neurodegenerative disorders.

The paper introduces Aion, a bistable anion-conducting channelrhodopsin with a long open state and precise light-switchable control, enabling extended neuronal silencing in Drosophila.

BiPOLES is an optogenetic tool that allows bidirectional control of neuronal activity using two different light colors, enabling both excitation and inhibition of the same neurons in a single experiment.

The paper identifies a somatosensory network in Drosophila larvae that uses neuropeptide action to gate specific escape behaviors based on sensory input type.

The paper shows that Tao kinase regulates synaptic growth and connectivity in Drosophila nociceptive circuits to maintain specificity and function during larval development.

The paper engineers anion-conducting channelrhodopsins with tunable spectra and kinetics for optogenetic control of behavior.