Author

Lorena Sofía López-Zepeda

Max Delbrück CenterORCID 0000-0001-9764-0984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Uwe OhleriD· 2 shared Alexis MorrisseyiD· 1 shared Antje Hirsekorn· 1 shared Begüm AydıniD· 1 shared Che‐Wei HsuiD· 1 shared Congyi LuiD· 1 shared Dubravka VučićevićiD· 1 shared Esteban O. MazzoniiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Uwe OhlerORCID

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2 papers

Recent·Most cited

GenomicsCell GenomicsPeer-reviewedSep 1, 2025

Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation

Dubravka Vučićević, Che‐Wei Hsu, Lorena Sofía López-Zepeda…·Uwe Ohler

The paper identifies CRISPRa-responsive enhancers and their target genes in a 2 Mb region around PHOX2B using TESLA-seq, revealing both known and novel regulatory relationships.

DOI 10.1016/j.xgen.2025.100984

humanCRISPR screen

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Developmental BiologybioRxivPreprintNov 23, 2020

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II atpro-differentiation genes

Görkem Garipler, Congyi Lu, Alexis Morrissey…·Esteban O. Mazzoni

A CRISPR screen identifies ZBTB11 and ZFP131 as factors maintaining pluripotency by pausing POL II at pro-differentiation genes.

3 citations

mouseexperimental assay

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