Author

Begüm Aydın

New York UniversityORCID 0000-0002-7066-5257Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Esteban O. MazzoniiD· 2 shared Shaun MahonyiD· 2 shared Alexis MorrisseyiD· 1 shared Chun‐Jun GuoiD· 1 shared Congyi LuiD· 1 shared Daniel MucidaiD· 1 shared Divyanshi SrivastavaiD· 1 shared Görkem Garipler· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioinformatics

Esteban O. MazzoniORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 15, 2024

Gut bacteria-derived succinate induces enteric nervous system regeneration

Begüm Aydın, Izabela Mamede, Joana Cardoso…·Daniel Mucida

The paper identifies gut bacteria-derived succinate as a key metabolite that promotes enteric nervous system regeneration after antibiotic-induced dysbiosis.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky

BioinformaticsGenome biologyPeer-reviewedJan 7, 2021

An interpretable bimodal neural network characterizes the sequence and preexisting chromatin predictors of induced TF binding

Divyanshi Srivastava, Begüm Aydın, Esteban O. Mazzoni, Shaun Mahony

The paper develops Bichrom, a bimodal neural network that models sequence and preexisting chromatin data to predict TF-DNA binding and shows preexisting chromatin improves binding specificity prediction for some TFs.

25 citations

ChIP-seqdeep learning

𝕏 PostBluesky

Developmental BiologybioRxivPreprintNov 23, 2020

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II atpro-differentiation genes

Görkem Garipler, Congyi Lu, Alexis Morrissey…·Esteban O. Mazzoni

A CRISPR screen identifies ZBTB11 and ZFP131 as factors maintaining pluripotency by pausing POL II at pro-differentiation genes.

3 citations

mouseexperimental assay

𝕏 PostBluesky