Author
Institut CurieORCID 0000-0003-1466-0950Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Ronan Flippot, Amélie Roehrig, Julien Vibert…·Yohann Loriot
This study uses single-cell RNA sequencing to analyze metastatic urothelial carcinoma and identifies macrophage-driven resistance to PD-(L)1 blockade as a key mechanism.
Yuna Landais, Juliette Bertorello, Marta Puerto…·Céline Vallot
This paper develops a single-nucleus multimodal framework to analyze transcriptional and histone modification landscapes in ovarian cancer, revealing epigenomic priming of chemoresistant states and its impact on treatment outcomes.
Brian J. Haas, Anne Van Arsdale, Alexander Dobin…·Aziz M. Al’Khafaji
The paper develops a tool to detect viral integrations in human genomes and applies it to over 30,000 tumor samples, identifying virus-human chimeric transcripts and insertion hotspots.
Erlend I. F. Fossen, Mauricio Moreira-Soares, Marissa LeBlanc…·Stefano Cavalieri
The paper externally validates five gene signatures in head and neck cancer patients, showing their prognostic and predictive value for treatment outcomes.
Galina Boldina, Maricarmen Vallejos, Delphine Allard…·Stéphan Vagner
The paper shows that intronic polyadenylation (IPA) of MET affects tumour progression and therapy resistance by producing a short MET isoform that reduces invasiveness and enhances response to MAPK-targeted therapy.