Orestes A. Carpaij

The paper identifies a novel asthma-associated epithelial differentiation trajectory involving KRT14+ basal cells and hillock-like cells that contributes to airway inflammation and remodelling in childhood-onset asthma.

The paper compares collagen organization and crosslinking in IPF and NR-ARDS, finding differences in collagen maturity despite similar collagen content.

FastCAR corrects ambient RNA contamination in scRNA-Seq data, improving the accuracy of differential gene expression analysis by reducing false positives.

This study examines the RSV response in bronchial epithelial cells from asthma patients and healthy donors, finding impaired antiviral responses in goblet and multiciliated cells in asthma.

The paper identifies three nasal DNA methylation CpG sites that predict childhood allergic disease with high accuracy, validated across Dutch and US Hispanic children.