Linda Lopez

Atypical genomic cortical patterning in autism with poor early language outcome

The paper identifies atypical genomic cortical patterning in autistic toddlers with poor early language outcome, linking it to prenatal developmental processes and later functional specialization.

Multiple freeze-thaw cycles lead to a loss of consistency in poly(A)-enriched RNA sequencing

This study quantifies how repeated freeze-thaw cycles affect RNA-Seq reliability, showing that poly(A)-enriched samples lose reproducibility after three cycles.

A perturbed gene network containing PI3K/AKT, RAS/ERK, WNT/β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity

The paper identifies a perturbed gene network in leukocytes linked to ASD genetics and symptom severity through analysis of transcriptomics data from toddlers.