Arjana Begzati

Pulmonary primary oxysterol and bile acid synthesis as a predictor of outcomesin pulmonary arterial hypertension

The paper identifies pulmonary primary oxysterol and bile acid synthesis as a prognostic biomarker for pulmonary arterial hypertension, outperforming current clinical risk scores.

Isotope tracing-based metabolite identificationfor mass spectrometry metabolomics

This paper introduces a method using isotope tracing and mass isotopomer distributions to identify novel metabolites in mass spectrometry data, achieving 62% identification of unknown peaks.

mRNA-Protein Coordination is Contextualized by Metastatic Biological Phenotypes

The paper shows that integrating mRNA and protein data improves understanding of metastasis by leveraging complementary and reinforcing signals between modalities.

Multiple freeze-thaw cycles lead to a loss of consistency in poly(A)-enriched RNA sequencing

This study quantifies how repeated freeze-thaw cycles affect RNA-Seq reliability, showing that poly(A)-enriched samples lose reproducibility after three cycles.