Cian O’Connor

Biomimetic miR-133a inhibitor activated scaffolds optimised for spinal cord repair promote neurite outgrowth and angiogenesis via neuronal cytoskeletal remodelling

This paper develops a biomimetic scaffold that inhibits miR-133a to promote neurite outgrowth and angiogenesis in spinal cord repair through cytoskeletal remodelling.

Scaffold-mediated miRNA-155 inhibition promotes regenerative macrophage polarisation leading to anti-inflammatory, angiogenic, and neurogenic responses for wound healing

This paper introduces a miRNA-155 inhibitor-activated scaffold that promotes anti-inflammatory, angiogenic, and neurogenic responses in chronic wounds through macrophage polarisation and nerve regeneration.

2D Boron Nanoplatelets as a Multifunctional Additive for Osteogenic, Gram-Negative Anti-Microbial and Mechanically Reinforcing Bone Repair Scaffolds

This paper demonstrates that 2D boron nanoplatelets enhance osteogenesis, anti-microbial properties, and mechanical strength in collagen scaffolds for bone repair.

PolyGraph - Flexible, Biocompatible & Electrically Optimised Graphene-Polymer Composites for Next-Generation Neural Interfaces

This paper introduces PolyGraph, a biocompatible graphene-polycaprolactone composite with low impedance and high charge injection capacity, demonstrating bidirectional neural interfacing in murine brain slices.