S. Browne

This paper develops a collagen-GAG scaffold delivering miRNA-29b to reduce fibrosis by inhibiting myofibroblast activation and ECM accumulation in wound healing.

This paper introduces a miRNA-155 inhibitor-activated scaffold that promotes anti-inflammatory, angiogenic, and neurogenic responses in chronic wounds through macrophage polarisation and nerve regeneration.

This study evaluates two β-cell network models, introduces heterogeneity based on single-cell gene expression, and incorporates paracrine signaling to improve physiological realism.

This study investigates how intrinsic metabolic and electrophysiologic properties and ionic coupling contribute to the beta hub cell phenotype in pancreatic islets.

Embedding day-8 cerebral organoids in Geltrex loaded with human brain microvascular endothelial cells, plus VEGF-supplemented mixed media, yields integrated endothelial networks and almost three-fold less apoptosis.

This study investigates how GLP-1R signaling shapes β-cell heterogeneity by analyzing calcium dynamics in islets from different mouse models and humanized KO mice.