Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers
Bettina Dietmair, James Humphries, Tim R. Mercer, Kristofer J. Thurecht, Christopher B. Howard, Seth W. Cheetham
This paper introduces a method using bispecific antibodies to deliver mRNA-LNPs to specific cell types, demonstrating efficient targeting of EGFR and PSMA positive cells.
Molecular Therapy — Nucleic Acids · Mar 19, 2025Peer-reviewedMolecular Biology