Kristofer J. Thurecht

A modular encapsulation system for precision delivery of proteins, nucleic acids and small molecules

This paper introduces caveospheres, a modular nanovesicle system for targeted delivery of various cargo, demonstrating efficacy in both in vitro and in vivo applications.

A Standardized Protocol to Investigate Trans-Endothelial Trafficking in Zebrafish: Nano-bio Interactions of PEG-based Nanoparticles in Live Vasculature

This paper develops a standardized protocol to assess nanoparticle trans-endothelial trafficking in zebrafish, identifying transport mechanisms for PEG-based nanoparticles.

Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers

This paper introduces a method using bispecific antibodies to deliver mRNA-LNPs to specific cell types, demonstrating efficient targeting of EGFR and PSMA positive cells.