Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson's disease
Amalie Holm Nygaard, Alrik L. Schörling, Zehra Abay-Nørgaard, Erno Hänninen, Yuan Li, Adrián Ramón Santonja, Gaurav Singh Rathore, Alison Salvador, Charlotte Rusimbi, Katrine Bech Lauritzen, Yu Zhang, Agnete Kirkeby
This study identifies FGF17 as a potent inducer of ventral midbrain dopaminergic progenitors, which can functionally rescue motor deficits in a rat Parkinson's disease model.
Stem Cells · Feb 17, 2025Peer-reviewedDevelopmental Biology