Author

Charlotte Rusimbi

University of CopenhagenORCID 0009-0002-1500-4648Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 2 Research Focus:drug response / drug discovery· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnete KirkebyiD· 3 shared Gaurav Singh RathoreiD· 3 shared Amalie Holm NygaardiD· 2 shared Barbara TreutleiniD· 2 shared Erno Hänninen· 2 shared Fátima Sanchís-CallejaiD· 2 shared J. Gray CampiD· 2 shared Pedro RifesiD· 2 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersDevelopmental Biology

Agnete KirkebyORCID

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4 papers

Recent·Most cited

Developmental BiologyNature MethodsPeer-reviewedDec 15, 2025

Decoding morphogen patterning of human neural organoids with a multiplexed single-cell transcriptomic screen

Fátima Sanchís-Calleja, Nadezhda V. Azbukina, Akanksha Jain…·Barbara Treutlein

The paper uses a multiplexed single-cell transcriptomic screen to study how morphogen cues affect regional specification in human neural organoids, finding that timing, concentration, and combination of morphogens strongly influence cell type and regional composition.

29 citationstop 1%

humanscRNA-seq

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NeurosciencebioRxivPreprintMay 23, 2025

Mapping early patterning events in human neural development usingan in-vitro microfluidic stem cell model

Gaurav Singh Rathore, Matias Ankjær, Pedro Rifes…·Agnete Kirkeby

The paper uses a microfluidic stem cell model to study early human neural patterning, identifying regional specification and fate determination during the epiblast stage.

4 citations

humanscRNA-seq

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Molecular BiologyMolecular CellPeer-reviewedMay 1, 2025

PAF1C allosterically activates CDK12/13 kinase during RNAPII transcript elongation

David López Martínez, Izabela Todorovski, Melvin Noé González…·Jesper Qualmann Svejstrup

The paper shows PAF1C allosterically activates CDK12/13 kinase to phosphorylate RNA polymerase II CTD during transcript elongation.

21 citationstop 2%

humanexperimental assay

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Developmental BiologyStem CellsPeer-reviewedFeb 17, 2025

Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson's disease

Amalie Holm Nygaard, Alrik L. Schörling, Zehra Abay-Nørgaard…·Agnete Kirkeby

This study identifies FGF17 as a potent inducer of ventral midbrain dopaminergic progenitors, which can functionally rescue motor deficits in a rat Parkinson's disease model.

4 citations

ratexperimental assay

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