Author

Ruxandra A. Lambuta

Institute of Molecular BiologyORCID 0000-0001-9810-1413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Approach:statistical model· 2

Frequent Co-Authors

Azza Soliman· 2 shared Marcel Misak· 2 shared Susanne GerberiD· 2 shared Anthony Y. SimoniD· 1 shared Audrey ForestiD· 1 shared C Verdel· 1 shared Chantal DesdouetsiD· 1 shared Daniel PiehiD· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPathology

Azza Soliman

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Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 27, 2026

DNA damage at Lamina-Associated Domains triggers nuclear envelope reorganization and chromatin detachment to prevent nuclear envelope blebbing and genome instability.

Diana Rubio-Contreras, Sylvain Audibert, Joanna Fernández…·Evi Soutoglou

DOI 10.64898/2026.10.25.761546

humanDNA methylation

𝕏 PostBluesky

Cell BiologyThe EMBO JournalPeer-reviewedSep 19, 2026

Whole genome duplication through mitotic slippage causes nuclear instability

Simon Gemble, Margot Budzyk, Anthony Y. Simon…·Renata Basto

The paper investigates how different routes to whole-genome duplication (WGD) affect nuclear stability, finding that mitotic slippage uniquely causes nuclear instability.

4 citationstop 1%

𝕏 PostBluesky

PathologybioRxivPreprintMay 8, 2026

16p11.2 Copy Number Variation Alters Genome Architecture and Transcriptional Regulation During Neurodevelopment

Marco Bertin, Marcel Misak, Mohit Navandar…·Susann Schweiger

This study investigates how 16p11.2 copy number variations affect genome architecture and transcription during neurodevelopment, finding both local dosage effects and broader chromatin changes.

DOI 10.64898/2026.05.07.723480

humanbulk RNA-seq

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BiophysicsbioRxivPreprintApr 2, 2026

Correcting Preprocessing Bias in Sparse Chromatin Contact Data Enables Physically Interpretable Reconstruction of Genome Architecture

Stanislav Sys, Marcel Misak, Azza Soliman…·Susanne Gerber

The paper identifies preprocessing bias in chromatin contact data and introduces a framework to correct it, enabling physically interpretable genome architecture reconstruction.

DOI 10.64898/2026.03.31.715622

Hi-Cdeep learning

𝕏 PostBluesky