Author

Natalia N. Gotmanova

Lomonosov Moscow State UniversityORCID 0000-0001-9838-9656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna V. BachevaiD· 2 shared Maria P. RubtsovaiD· 2 shared Alexander A. EzhoviD· 1 shared Andrey V. AraloviD· 1 shared Anna A. ValyaevaiD· 1 shared Boris P MyasnikoviD· 1 shared E. G. Belyaev· 1 shared Ekaterina A. GusevaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Anna V. BachevaORCID

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2 papers

Recent·Most cited

Neuronal cell line expressing full-length mutant huntingtin displays alteration of proteasome activity

Natalia N. Gotmanova, Tatiana V. Bobik, Alexander A. Ezhov, Anna A. Valyaeva, Maria I. Zvereva, Maria P. Rubtsova, Anna V. Bacheva

The paper demonstrates that neuronal cells expressing mutant huntingtin show altered proteasome activity and aggregate formation.

bioRxiv · Apr 5, 2026 · PreprintNeuroscience

Cyanine dye conjugates of a 2'-deoxycytidine-based auto- and mitophagy activator extend Caenorhabditis elegans lifespan

Ekaterina A. Guseva, Polina N. Kamzeeva, Sofya Y. Sokolskaya, Boris P Myasnikov, Julia A. Golubeva, Vera A. Alferova, Rose-Lys Zaranaina, Valeriya B. Vays, Irina M. Vangeli, E. G. Belyaev, Olga A. Potapova, Natalia N. Gotmanova, Anna V. Bacheva, Lora E. Bakeeva, Elena Marusich, , Andrey V. Aralov

The paper identifies a 2'-deoxycytidine-based compound that activates autophagy and mitophagy, extends C. elegans lifespan when conjugated with a mitochondria-targeting dye.

bioRxiv · Jan 25, 2026 · PreprintPharmacology & Toxicology