Author
Brigham and Women's HospitalORCID 0000-0001-9840-4692Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Raehoon Jeong, Martha L. Bulyk
The paper investigates why many GWAS loci linked to immune-mediated diseases lack eQTL colocalization by analyzing chromatin accessibility QTLs in LCLs and other immune cell types.
Jessica King, Stephen S. Gisselbrecht, Julie‐Alexia Dias…·Martha L. Bulyk
The paper identifies non-DNA-contacting residues that determine mono- versus bispecific DNA binding in forkhead transcription factors using protein binding microarrays.
Raehoon Jeong, Martha L. Bulyk
The paper identifies novel candidate genes and transcription factor variants associated with congenital heart defect and orofacial cleft through a gene burden analysis of parent-offspring trio cohorts.
Julie A. Jurgens, Paola M. Matos Ruiz, Jessica King…·Elizabeth C. Engle
The paper identifies three novel candidate genes for ocular congenital cranial dysinnervation disorders using zebrafish CRISPR screening and protein binding microarrays to assess variant functionality.
Kian Hong Kock, Patrick K. Kimes, Stephen S. Gisselbrecht…·Martha L. Bulyk
The paper analyzes DNA binding effects of 92 human homeodomain mutants, identifying 14 novel specificity-determining residues and highlighting limitations of variant effect prediction tools.
Raehoon Jeong, Martha L. Bulyk
The paper identifies 69 blood cell trait GWAS loci potentially driven by PU.1 occupancy variation and nominates 51 variants as causal through colocalization analysis with PU.1 bQTLs.