Author

Jessica King

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Elisabeth Rothman· 2 shared Martha L. BulykiD· 2 shared Raehoon JeongiD· 2 shared Adriano MagliiD· 1 shared Anne C. LietzkeiD· 1 shared Anne O’Donnell‐LuriaiD· 1 shared Ava M. Stendahl· 1 shared Belle A. Henry-Kanarek· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Elisabeth Rothman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Missense variants in human forkhead transcription factors reveal determinants of forkhead DNA bispecificity

Jessica King, Stephen S. Gisselbrecht, Julie‐Alexia Dias, Raehoon Jeong, Elisabeth Rothman, Martha L. Bulyk

The paper identifies non-DNA-contacting residues that determine mono- versus bispecific DNA binding in forkhead transcription factors using protein binding microarrays.

Cell Reports · Oct 21, 2025Peer-reviewedGenomics

Gene identification for ocular congenital cranial motor neuron disorders using human sequencing, zebrafish screening, and protein binding microarrays

Julie A. Jurgens, Paola M. Matos Ruiz, Jessica King, Emma E. Foster, Lindsay Berube, Wai Man Chan, Brenda J. Barry, Raehoon Jeong, Elisabeth Rothman, Mary C. Whitman, Sarah E. MacKinnon, Cristina Rivera Quiles, Brandon M. Pratt, Teresa Easterbrooks, Fiona M. Mensching, , Elizabeth C. Engle

The paper identifies three novel candidate genes for ocular congenital cranial dysinnervation disorders using zebrafish CRISPR screening and protein binding microarrays to assess variant functionality.

bioRxiv · Sep 12, 2024 · PreprintNeuroscience

Limitations in PPAR-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells

Anne C. Lietzke, Emily M. Walker, Elizabeth J. Bealer, Kelly M. Crumley, Jessica King, Ava M. Stendahl, Jie Zhu, Gemma L. Pearson, Elena Levi-D’Ancona, Belle A. Henry-Kanarek, Rebecca K. Davidson, Jin Li, Emma C. Reck, Yifei Wu, Manikanta Arnipalli, , Scott A. Soleimanpour

This study identifies PPAR-dependent mitochondrial programming as a limiting factor in the differentiation of human stem cell-derived β cells and shows that PPAR agonists can enhance β cell formation and function.

bioRxiv · Jul 26, 2024 · PreprintDevelopmental Biology