Author

Elisabeth Rothman

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Martha L. BulykiD· 3 shared Jessica King· 2 shared Raehoon JeongiD· 2 shared Adam FrankishiD· 1 shared Adriano MagliiD· 1 shared Alex S. HolehouseiD· 1 shared Anisa V. PrasadiD· 1 shared Anna BerensoniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenomics

Martha L. BulykORCID

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3 papers

Recent·Most cited

Missense variants in human forkhead transcription factors reveal determinants of forkhead DNA bispecificity

Jessica King, Stephen S. Gisselbrecht, Julie‐Alexia Dias, Raehoon Jeong, Elisabeth Rothman, Martha L. Bulyk

The paper identifies non-DNA-contacting residues that determine mono- versus bispecific DNA binding in forkhead transcription factors using protein binding microarrays.

Cell Reports · Oct 21, 2025Peer-reviewedGenomics

Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms

Luke Lambourne, Kaia Mattioli, Clarissa Stephanie Santoso, Gloria Sheynkman, Sachi Inukai, Babita Kaundal, Anna Berenson, Kerstin Spirohn, Anukana Bhattacharjee, Elisabeth Rothman, Shaleen Shrestha, Florent Laval, Brent S. Carroll, Stephen P. Plassmeyer, Ryan J. Emenecker, , Juan I. Fuxman Bass

The paper identifies two categories of transcription factor isoforms with distinct molecular functions and shows they contribute to gene regulatory complexity.

Molecular Cell · Mar 27, 2025Peer-reviewedSystems Biology

Gene identification for ocular congenital cranial motor neuron disorders using human sequencing, zebrafish screening, and protein binding microarrays

Julie A. Jurgens, Paola M. Matos Ruiz, Jessica King, Emma E. Foster, Lindsay Berube, Wai Man Chan, Brenda J. Barry, Raehoon Jeong, Elisabeth Rothman, Mary C. Whitman, Sarah E. MacKinnon, Cristina Rivera Quiles, Brandon M. Pratt, Teresa Easterbrooks, Fiona M. Mensching, , Elizabeth C. Engle

The paper identifies three novel candidate genes for ocular congenital cranial dysinnervation disorders using zebrafish CRISPR screening and protein binding microarrays to assess variant functionality.

bioRxiv · Sep 12, 2024 · PreprintNeuroscience