Author

Daisy Castillo-Guzman

University of California, DavisORCID 0000-0001-9849-2119Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

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Frederic L. ChediniD· 1 shared Lionel A. SanziD· 1 shared M. Hughson Frederick· 1 shared Stella R. HartonoiD· 1 shared Tadas SereivaiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Frederic L. ChedinORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintJun 8, 2020

SF3B1-targeted Splicing Inhibition Triggers Transcriptional Stress Response and Global Alterations in R-Loop Landscape

Daisy Castillo-Guzman, Stella R. Hartono, M. Hughson Frederick…·Frederic L. Chedin

This study shows that SF3B1 inhibition causes intron retention and R-loop changes, with R-loop gains linked to stress-response gene readthrough and not DNA damage.

21 citations

humanbulk RNA-seq

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