Molecular BiologybioRxivPreprint
Protein-mediated stabilization and nicking of the non-template DNA strand dramatically affect R-loop formation in vitro
Ethan T Holleman, Thomas E. Catley, Tadas Sereiva…·Frederic L. Chedin
This study shows that DNA-binding proteins and nicks increase R-loop formation in vitro, revealing their roles in R-loop dynamics and initiation.