Author

Ashley N. Brandebura

Salk Institute for Biological StudiesORCID 0000-0001-9862-0977Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrien PaumieriD· 2 shared Nicola J. AlleniD· 2 shared Antônio F. M. PintoiD· 1 shared James DengiD· 1 shared Jolene K. DiedrichiD· 1 shared Lara Labarta-BajoiD· 1 shared Mariel Kristine B MicaeliD· 1 shared Nick AndrewsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Adrien PaumierORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedApr 23, 2026

Suppression of astrocyte BMP signaling improves fragile X syndrome molecular signatures and functional deficits

James Deng, Adrien Paumier, Lara Labarta-Bajo…·Nicola J. Allen

This study shows suppressing BMP signaling in astrocytes reduces molecular and functional deficits in fragile X syndrome.

2 citationstop 3%

mouseproteomics

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NeuroscienceCell ReportsPeer-reviewedSep 18, 2025

Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down Syndrome

Ashley N. Brandebura, Adrien Paumier, Quinn N. Asbell…·Nicola J. Allen

This study identifies pleiotrophin dysregulation in astrocytes as a contributor to neuronal structural and functional deficits in Down Syndrome, showing potential for therapeutic intervention.

15 citationstop 1%

mouseexperimental assay

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