Mariel Kristine B Micael

ESCRT-0 regulates AMPA receptor currents and Ca2+- dependent signaling

This study shows that Hrs, an ESCRT-0 protein, modulates AMPA receptor currents and Ca2+-dependent signaling by sensing and responding to neuronal activity at synapses.

Developmental and age-related synapse elimination is mediated by glial Croquemort

This study identifies glial Croquemort as a key regulator of synapse elimination during development and aging in Drosophila.

Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down Syndrome

This study identifies pleiotrophin dysregulation in astrocytes as a contributor to neuronal structural and functional deficits in Down Syndrome, showing potential for therapeutic intervention.

Multi-omic analysis reveals the unique glycan landscape of the blood-brain barrier glycocalyx

The paper analyzes the BBB glycocalyx using multi-omic approaches, revealing unique glycan composition and structural features, and their potential role in neuroinflammation.