Synthetic BiologyNature CommunicationsPeer-reviewed
Engineering Cell Sensing and Responses Using a GPCR-Coupled CRISPR-Cas System
Nathan H. Kipniss, P.C. Dave P. Dingal, Timothy R. Abbott…·Lei S. Qi
This paper introduces CRISPR ChaCha, a GPCR-Coupled CRISPR-Cas system that converts extracellular signals into genetic programs, showing improved performance over existing systems.
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