Haifeng Wang

The paper shows PAX6 expression occurs post-replicatively during neuroectoderm differentiation, coupling NPC fate to cell cycle progression after DNA replication.

This paper develops valency-controlled receptors (VCRs) to enhance CAR functionality by modulating T cell signaling through multivalent ligands, showing improved immune response against tumors.

A single enzyme, TGM2, bidirectionally controls H3 monoaminylation dynamics, which, in turn, facilitate neural rhythmicity.

This study uses CRISPR-EChO to investigate HP1's role in organizing chromatin at supranucleosomal scales, revealing its ability to compact chromatin and repress transcription over large genomic regions.

This paper introduces CRISPR ChaCha, a GPCR-Coupled CRISPR-Cas system that converts extracellular signals into genetic programs, showing improved performance over existing systems.