Author

Gaëlle Pennarun

InsermORCID 0000-0001-9881-9345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Francesca CipressaiD· 2 shared Giovanni CenciiD· 2 shared Pascale BertrandiD· 2 shared Alessandro PaiardiniiD· 1 shared Chiara Borghi· 1 shared Claudia Di DioiD· 1 shared Didier BussoiD· 1 shared Giuseppe BossoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Francesca CipressaORCID

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2 papers

Recent·Most cited

Cell BiologyNucleic Acids ResearchPeer-reviewedAug 15, 2026

Lamin B1-dependent regulation of human separase in mitosis

Julien Picotto, Laureline Urli, Francesca Cipressa…·Gaëlle Pennarun

This study identifies lamin B1 as a regulator of separase activity during mitosis, showing that lamin B1 depletion or overexpression disrupts chromosome separation and centrosome stability.

1 citation

humanexperimental assay

𝕏 PostBluesky

GeneticsCell Death DiscoveryPeer-reviewedOct 21, 2025

An evolutionarily conserved role for separase in the regulation of nuclear lamins

Francesca Cipressa, Gaëlle Pennarun, Giuseppe Bosso…·Giovanni Cenci

This study shows that separase interacts with nuclear lamins in Drosophila and humans, affecting nuclear organization and lamin levels, indicating an evolutionarily conserved role.

1 citation

Drosophilahuman

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