PathologyProceedings of the National Academy of SciencesPeer-reviewed
LRG1 promotes atherosclerosis by activating macrophages
Juan Wang, Jing Wang, Jiuchang Zhong…·Xiaodong Wang
This study identifies LRG1 as a pro-inflammatory factor in atherosclerosis by promoting macrophage M1 polarization through ERK and JNK pathways, and shows that LRG1 inhibition reduces atherosclerosis progression.
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