Digby Francis Warner

This paper demonstrates that mycobacteriophage D29-mediated lysis improves genomic DNA recovery from low-biomass mycobacterial samples compared to the CTAB method.

This study shows that culture filtrate selectively enhances Mycobacterium tuberculosis growth from low inoculum densities, but its effect diminishes at higher densities, suggesting limitations in current culturing methods.

This study identifies compounds from Berberis holstii that inhibit Mycobacterium tuberculosis efflux pumps, showing synergistic effects with spectinomycin.

Deleting early riboflavin genes (ribA2 in both species, ribG in M. smegmatis) sharply reduced MAIT cell activation, while ribH deletion raised recognition of M. tuberculosis only.

This study investigates riboflavin biosynthesis and utilization in mycobacteria by creating conditional knockdowns and analyzing their impact on viability and MAIT cell recognition.

This study introduces CRISPRi-Seq for essential gene and transcriptional unit identification in mycobacteria, showing strong overlap with Tn-Seq and functional validation of operon structure.