Lyandysha V. Zholudeva

This study shows that embryonic spinal cord transplants improve diaphragm function after cervical SCI but lose connectivity over time, reducing long-term effectiveness.

The paper demonstrates a synthetic dual-moiety strategy to design CXCR4 agonist peptides that mimic SDF-1, showing therapeutic benefit in a mouse model of ALS through neuroprotection.

The paper shows that lineage origins shape gene regulation and function in V2a neurons, identifying key regulators specific to posterior identities.

This study investigates the reprogramming of astrocytes to neurons in spinal cord injury, showing higher in vitro efficiency than in vivo.

This study shows that human cervical V2a interneurons transplanted into injured spinal cords form functional synaptic connections with host tissue, improving diaphragm activity.

The paper uses single-cell multimodal analyses to show how maternal diabetes alters epigenomic and transcriptomic states in cardiac and craniofacial progenitors, leading to developmental defects.

This paper demonstrates allele-specific CRISPR gene editing in a human CMT2E model rescues disease pathology by inactivating the mutant NEFL allele.