Author

Peter W. Baas

Drexel UniversityORCID 0000-0002-1272-4538Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Liang QiangiD· 2 shared Xiaohuan SuniD· 2 shared Emanuela PiermariniiD· 1 shared Huaqiang Cao· 1 shared Itzhak FischeriD· 1 shared James J. CaiiD· 1 shared Kazuhito Toyo‐okaiD· 1 shared Ma JiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Liang QiangORCID

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Author profile →

4 papers

Recent·Most cited

Analyses of exon 4a structure reveal unique properties of Big tau

Itzhak Fischer, Peter W. Baas

The paper analyzes the biophysical properties of exon 4a in tau proteins, showing it introduces a highly acidic, hydrophilic module that reduces aggregation potential compared to LMW tau.

bioRxiv · Sep 4, 2025 · PreprintNeuroscience

Genotype-Phenotype Distinctions in Spastic Paraplegia 4 Reveal HDAC6 as a Therapeutic Target

Neha Mohan, Skandha Ramakrishnan, Xiaohuan Sun, Ying Sun, Theresa M. Connors, Victor Z. Chai, Emanuela Piermarini, Peter W. Baas, James J. Cai, Mei Liu, Liang Qiang

This study uses isogenic hiPSC-derived motor cortical organoids to identify HDAC6 hyperactivation as a key driver of SPG4 pathology and a potential therapeutic target.

bioRxiv · Jul 15, 2025 · PreprintNeuroscience

Antagonistic Roles of Tau and MAP6 in Regulating Neuronal Development

Xiaohuan Sun, Wenqian Yu, Peter W. Baas, Kazuhito Toyo‐oka, Liang Qiang

The paper shows tau and MAP6 have opposing roles in neuronal development by regulating microtubule stability and dynamics in cultured neurons and in vivo.

Journal of Cell Science · Sep 11, 2024Peer-reviewedCell Biology

ASD mutation of Katnal2 impairs ependymal ciliary motion and causes hydrocephalus

Shuai Qiu, Huaqiang Cao, Xue Yao, Wenlong Zhao, Shuangyi Xie, Nan Wu, Meilin Song, Yi-Hsuan Pan, Peter W. Baas, Ma Ji, Xiao‐bing Yuan

The paper shows that an ASD-linked mutation in Katnal2 impairs ependymal ciliary motion, causing hydrocephalus and behavioral deficits in mice.

bioRxiv · Jul 3, 2023 · PreprintNeuroscience