Author

Juan Luis Mateo

Universidad de OviedoORCID 0000-0001-9902-6048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:zebrafish· 3 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Joachim WittbrodtiD· 2 shared Max D. Knickmeyer· 2 shared Stephan HeermanniD· 2 shared Aimée ZúñigaiD· 1 shared Alex CorneaniD· 1 shared Belal RahhaliD· 1 shared Bettina WelziD· 1 shared Eleni RoussaiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Joachim WittbrodtORCID

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3 papers

Recent·Most cited

Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction

Alex Cornean, Jakob Gierten, Bettina Welz, Juan Luis Mateo, Thomas Thumberger, Joachim Wittbrodt

The paper develops a base editing framework in medaka and zebrafish to functionally validate SNVs, demonstrating its application in recreating cardiac phenotypes and validating candidate genes for congenital heart disease.

eLife · Apr 4, 2022Peer-reviewedGenetics

BMP signaling interferes with optic chiasm formation and retinal ganglion cell pathfinding in zebrafish

Max D. Knickmeyer, Juan Luis Mateo, Stephan Heermann

This study shows that BMP signaling disrupts optic chiasm formation and retinal ganglion cell (RGC) pathfinding in zebrafish by affecting midline guidance cues and optic stalk morphogenesis.

International Journal of Molecular Sciences · Apr 27, 2021Peer-reviewedDevelopmental Biology

TGF(beta) Mediated Structural Remodeling Facilitates Optic Fissure Fusion And The Necessity Of BMP Antagonism In This Process

Max D. Knickmeyer, Juan Luis Mateo, Priska Eckert, Eleni Roussa, Belal Rahhal, Aimée Zúñiga, Kerstin G. KRIEGLSTEIN, Joachim Wittbrodt, Stephan Heermann

This study identifies TGF{beta} as essential for optic fissure fusion, with BMP antagonists preventing excessive BMP signaling to facilitate closure.

Open Biology · Mar 1, 2018Peer-reviewedDevelopmental Biology