Author

Jacklyn M. Newsome

University of California San DiegoORCID 0000-0001-9908-5750Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:scATAC-seq· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant effect prediction· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Joshua ChiouiD· 3 shared Kyle J. GaultoniD· 3 shared Anthony AylwardiD· 2 shared Jaspreet KauriD· 2 shared Mei-Lin Okino· 2 shared Paola Benaglio· 2 shared Sebastian PreißliD· 2 shared Sierra CorbaniD· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersGenomics

Joshua ChiouORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GenomicsCell GenomicsPeer-reviewedNov 11, 2022

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

Paola Benaglio, Han Zhu, Mei-Lin Okino…·Kyle J. Gaulton

The paper identifies T1D risk genes and regulatory elements that influence beta cell survival under proinflammatory cytokine exposure using functional genomics and genetics.

33 citations

humanATAC-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintDec 3, 2020

Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex trait variants using single nucleus ATAC-seq

Paola Benaglio, Jacklyn M. Newsome, Jee Yun Han…·Kyle J. Gaulton

The paper uses snATAC-seq to map chromatin accessibility QTLs in immune cell types and fine-maps complex trait loci, identifying cell type-specific causal variants.

7 citations

humanscATAC-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 12, 2020

Single Nucleus Multiomic Profiling Reveals Age-Dynamic Regulation of Host Genes Associated with SARS-CoV-2 Infection

Allen Wang, Joshua Chiou, Olivier Poirion…·Xin Sun

The paper uses single nucleus ATAC-seq and RNA-seq to show age-related changes in chromatin accessibility and gene expression linked to SARS-CoV-2 entry genes in human lung cells.

21 citations

humanscATAC-seq

𝕏 PostBluesky