Caroline M. Mitchell

This study examines how rituximab treatment affects vaginal mucosal immune markers, immune cell populations, and microbiome composition in women compared to healthy controls.

Endolysin BNT331 combined with Lactobacillus crispatus reduces bacterial load and suppresses inflammation in a human vagina chip model of bacterial vaginosis.

This study identifies beta-carboline compounds produced by vaginal lactobacilli that reduce inflammation by suppressing immune signaling pathways and demonstrate therapeutic potential in a mouse model.

The paper introduces a strategy for analyzing matched-set microbiome data using PERMANOVA and LDM, showing improved performance in simulations and real-world applications.