Yi Lu

This study identifies two distinct genetic factors underlying creativity, showing different genetic correlations with education and psychiatric disorders.

The paper identifies biologically distinct subtypes of MDD based on energy-related symptoms and finds genetic and metabolic differences between them.

This study identifies 52 genetic variants associated with adolescent-onset depression through a large GWAS, revealing age-specific mechanisms and potential drug targets.

The paper integrates genomic data with single-cell transcriptomics to identify brain cell types and regions associated with psychiatric disorders and traits.

This study identifies genetic variants associated with antisocial behavior through a genome-wide association meta-analysis, finding significant links to FOXP2 and correlations with multiple health and behavioral traits.

This study performs a genome-wide association study of frailty index to identify genetic signals and pathways, finding synapse function enrichment and associations with educational attainment.

This study conducts a genome-wide association meta-analysis of childhood aggression across multiple raters, instruments, and ages, identifying genetic correlations with various traits but no genome-wide significant SNPs.

This study identifies 12 genetic loci associated with loneliness and finds genetic correlations with 34 health outcomes, including cardiovascular and psychiatric disorders.

This study investigates genetic links between asthma and affective traits, finding shared genetic influences between asthma and depression, and neuroticism, but not anxiety.

This study investigates the association between rare copy number variants (CNVs) and neurodevelopmental problems (NPs) in children, finding sex-specific effects in anxiety/depression.

This study evaluates ADHD genetic risk variants' association with general psychopathology and specific neurodevelopmental traits, finding general pleiotropy and a specific link to hyperactivity/impulsivity.

This study finds genetic overlap between adolescent psychotic experiences and schizophrenia, bipolar disorder, and major depression using polygenic risk scores and genome-wide association analyses.

The paper finds genetic correlations between psychiatric disorders and related continuous traits in a Swedish twin sample, suggesting disorders are extreme ends of continuous traits.